PRODUCT DETAILS

About Actizo 20 mg/120 mg Tablet

ARTEMETHER+LUMEFANTRINE belongs to the class of 'anti-malarial drugs', primarily used to treat and prevent malaria. Malaria is a disease caused by a plasmodium parasite, transmitted by the bite of infected Anopheles mosquitoes. When an infected mosquito bites a healthy person, it transmits the 'Plasmodium parasite' into the bloodstream, which affects the red blood cells and liver cells. Malaria symptoms usually start in 10 days to 4 weeks after the infection. They include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma and bloody stools.

ARTEMETHER+LUMEFANTRINE contains two medicines, namely: Artemether and Lumefantrine. These are anti-malarial drugs that interfere with Plasmodium parasite's growth in the red blood cells of the human body. ARTEMETHER+LUMEFANTRINE is a combination that is used to treat non-severe malaria caused by a parasite called 'Plasmodium falciparum,' other Plasmodium species. It works by inhibiting nucleic acid and protein synthesis in Plasmodium falciparum. Artemether is known to reduce parasite biomass and Lumefantrine eliminates residual parasites.

Uses of Actizo 20 mg/120 mg Tablet

Malaria

Medicinal Benefits of Actizo 20 mg/120 mg Tablet

ARTEMETHER+LUMEFANTRINE contains two anti-malarial drugs, namely: Artemether and Lumefantrine. It is a combination that treats non-severe malaria caused by a parasite called 'Plasmodium falciparum', other Plasmodium species. It interferes with the growth of Plasmodium parasites in the red blood cells of the human body. ARTEMETHER+LUMEFANTRINE works by inhibiting nucleic acid and protein synthesis in Plasmodium falciparum. Artemether reduces parasite biomass and Lumefantrine eliminates residual parasites.

Directions for Use

ARTEMETHER+LUMEFANTRINE is available in oral tablet formulation. Tablet: Take ARTEMETHER+LUMEFANTRINE with food to avoid stomach upset. Swallow ARTEMETHER+LUMEFANTRINE as a whole with a glass of water, do not chew or break the tablet. For patients like infants and children who cannot swallow the tablets, crush the tablet and mix it with 1 to 2 teaspoons of water in a clean container and administer. Rinse the container with more water and swallow the contents. You can also give the crushed tablet preparation with food/drink like milk, formula, pudding, broth and porridge.

Side Effects of Actizo 20 mg/120 mg Tablet

• Headache
• Dizziness
• Loss of appetite
• Weakness
• Fever
• Chills
• Tiredness
• Muscle/joint pain
• Nausea
• Vomiting
• Abdominal pain
• Cough
• Trouble sleeping

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Let your doctor know if you use any antibiotic drugs or have recently undergone treatment with other anti-malarial drugs. Inform your doctor if you have any allergic reactions to ARTEMETHER+LUMEFANTRINE or its components. Brief your medical history to the doctor if you have any liver or kidney problems, malarial infection of the brain, lungs or kidneys, severe heart diseases and electrolyte imbalance. It is essential to inform your doctor if you have hypokalemia (low potassium levels) or hypomagnesemia (low magnesium levels) before starting ARTEMETHER+LUMEFANTRINE. ARTEMETHER+LUMEFANTRINE may affect QT prolongation that can cause serious fast/irregular heartbeat. Hence it is advised to inform your doctor if you have any heart-related problems like heart failure, slow heartbeat, QT prolongation in EKG or ECG (electrocardiogram), and a family history of heart diseases. ARTEMETHER+LUMEFANTRINE is not recommended during the first three months of pregnancy. Do not use ARTEMETHER+LUMEFANTRINE during breastfeeding. Once you have completed the course, you should wait at least one week before starting to breastfeed again. However, it is essential to let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother. Avoiding alcohol is recommended to rule out any possibility of side effects like dizziness or drowsiness.